Sean Eddy

Sean R. Eddy

Sean R. Eddy
Fields bioinformatics
Institutions Howard Hughes Medical Institute (HHMI) Janelia Farm Research Campus
Alma mater California Institute of Technology, University of Colorado, Medical Research Council
Academic advisors John Sulston, Richard Durbin
Known for HMMER[1], Infernal[2], Pfam[3] and Rfam
Notable awards Benjamin Franklin Award (Bioinformatics)

Sean R. Eddy is a scientist who leads a research group at the Howard Hughes Medical Institute (HHMI) Janelia Farm Research Campus[4] in Virginia, with interests in bioinformatics, computational biology and biological sequence analysis.[5][6][7] Current projects include the use of Hidden Markov models[8][9] in HMMER, Infernal[10] Pfam and Rfam.[11]

In 2007, Sean was the winner of the Benjamin Franklin Award in Bioinformatics for contributions to Open Access in the Life Sciences.[12]

Education and employment

Sean completed a Bachelor of Science in Biology at California Institute of Technology in 1986,[13] followed by a Ph.D in molecular biology at the University of Colorado in 1991. From 1992 to 1995 he was a postdoctoral fellow at the Medical Research Council (MRC) Laboratory of Molecular Biology (LMB) in Cambridge UK working with John Sulston and Richard Durbin. From 1995 to 2007 he worked at Washington University School of Medicine and has been working for the Howard Hughes Medical Institute since 2000. He graduated June, 1982 from Marion Center Area High School, Marion Center, PA.

Sources and notes

  1. ^ Finn, R. D.; Clements, J.; Eddy, S. R. (2011). "HMMER web server: Interactive sequence similarity searching". Nucleic Acids Research 39 (Web Server issue): W29–W37. doi:10.1093/nar/gkr367. PMC 3125773. PMID 21593126. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3125773.  edit
  2. ^ Nawrocki, E. P.; Kolbe, D. L.; Eddy, S. R. (2009). "Infernal 1.0: Inference of RNA alignments". Bioinformatics 25 (10): 1335–1337. doi:10.1093/bioinformatics/btp157. PMC 2732312. PMID 19307242. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2732312.  edit
  3. ^ Bateman, A.; Coin, L.; Durbin, R.; Finn, D.; Hollich, V.; Griffiths-Jones, S.; Khanna, A.; Marshall, M. et al. (Jan 2004). "The Pfam protein families database" (Free full text). Nucleic Acids Research 32 (Database issue): 138D–1141. doi:10.1093/nar/gkh121. ISSN 0305-1048. PMC 308855. PMID 14681378. http://nar.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=14681378.  edit
  4. ^ http://www.hhmi.org/research/groupleaders/eddy_bio.html HHMI Scientist Biography: Sean R. Eddy, Ph.D.
  5. ^ Durbin, Richard M.; Eddy, Sean R.; Krogh, Anders; Mitchison, Graeme (1998), Biological Sequence Analysis: Probabilistic Models of Proteins and Nucleic Acids (1st ed.), Cambridge: Cambridge University Press, ISBN 0-521-62971-3, http://www.cambridge.org/gb/knowledge/isbn/item1158701 
  6. ^ Lander, Eric S.; Linton, M. .; Birren, B. .; Nusbaum, C. .; Zody, C. .; Baldwin, J. .; Devon, K. .; Dewar, K. . et al. (Feb 2001). "Initial sequencing and analysis of the human genome". Nature 409 (6822): 860–921. doi:10.1038/35057062. ISSN 0028-0836. PMID 11237011.  edit
  7. ^ http://selab.janelia.org/people/eddys/ Sean Eddy's homepage
  8. ^ Eddy, S. R. (2004). "What is a hidden Markov model?". Nature Biotechnology 22 (10): 1315–1316. doi:10.1038/nbt1004-1315. PMID 15470472.  edit
  9. ^ Eddy, S. (1998). "Profile hidden Markov models". Bioinformatics (Oxford, England) 14 (9): 755–763. PMID 9918945.  edit
  10. ^ http://cryptogenomicon.org Sean Eddy's blog
  11. ^ http://www.ncbi.nlm.nih.gov/pubmed?term=sean%20eddy%5Bau%5D Sean Eddy publications in PubMed
  12. ^ http://blogs.openaccesscentral.com/blogs/bmcblog/entry/sean_eddy_wins_open_access BioMed Central Blog: Sean Eddy wins open access award
  13. ^ http://selab.janelia.org/people/eddys/cv.pdf Sean Eddy CV